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Msh2tm1Tts
Targeted Allele Detail
Summary
Symbol: Msh2tm1Tts
Name: mutS homolog 2; targeted mutation 1, Teruhisa Tsuzuki
MGI ID: MGI:2389314
Synonyms: MSH2-
Gene: Msh2  Location: Chr17:87979960-88031141 bp, + strand  Genetic Position: Chr17, 57.87 cM
Alliance: Msh2tm1Tts page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79732
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsA portion of exon 13 and all of exon 14 were replaced by a neomycin selection cassette inserted by homologous recombination. (J:79732)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msh2 Mutation:  95 strains or lines available
References
Original:  J:79732 Egashira A, et al., Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes. DNA Repair (Amst). 2002 Nov 3;1(11):881-93
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory