Fembrs5^SJL/J
QTL Variant Detail

Summary

• QTL variant: Fembrs5^SJL/J
• Name: femur breaking strength 5; SJL/J
• MGI ID: MGI:2389086
• QTL: Fembrs5 Location: Chr1:184462514-184462658 bp Genetic Position: Chr1, cM position of peak correlated region/allele: 88.97 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: SJL/J

Variant description

• Allele Type: QTL
• Inheritance: Other (see notes)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Notes

Fembrs5 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:76508

119 polymorphic markers were screened in 633 (MRL/MpJ x SJL/J)F2 female animals to detect loci associated with femur bone mineral density. 7-week old female animals were used for the study. Fembrs5 was identified on mouse Chromosome 1 with LOD=5.2 at D1Mit291.

References

• Original: J:76508 Li X, et al., Genetic Dissection of Femur Breaking Strength in a Large Population (MRL/MpJxSJL/J) of F2 Mice: Single QTL Effects, Epistasis, and Pleiotropy. Genomics. 2002 May;79(5):734-40
• All: 1 reference(s)