Tg(APOE-IL17E)1Mkim
Transgene Detail

Summary

• Symbol: Tg(APOE-IL17E)1Mkim
• Name: transgene insertion 1, Mee Rhan Kim
• MGI ID: MGI:2388946
• Transgene: Tg(APOE-IL17E)1Mkim Location: unknown
• Alliance: Tg(APOE-IL17E)1Mkim page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOE-IL17E)1Mkim expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IL25 (64806)

  Il25	(MGI:2155888)

• Mutation details: The transgene consists of a 483 bp full-length human IL17E cDNA, the liver-specific APOE promoter, hepatic control region (HCR), and an SV40 polyadenylation site. Transgene expression was verified by Northern and Western blot analysis of liver extracts from transgenic animals. (J:79373)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:79373 Kim MR, et al., Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood. 2002 Oct 1;100(7):2330-40
• All: 1 reference(s)