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Myctm1Jlc
Targeted Allele Detail
Nomenclature
Symbol: Myctm1Jlc
Name: myelocytomatosis oncogene; targeted mutation 1, John L Cleveland
MGI ID: MGI:2388702
Synonyms: c-myc-
Gene: Myc  Location: Chr15:61985391-61990374 bp, + strand  Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79427
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was disrupted by the insertion of a gpt selection cassette. Expression analysis of homozygous mutant ES cells indicated an absence of protein product. (J:4556)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myc Mutation:  26 strains or lines available
References
Original:  J:79427 Baudino TA, et al., c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes Dev. 2002 Oct 1;16(19):2530-43
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory