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Targeted Allele Detail
Symbol: Gdi1tm1Toni
Name: guanosine diphosphate (GDP) dissociation inhibitor 1; targeted mutation 1, Daniela Toniolo
MGI ID: MGI:2388605
Gene: Gdi1  Location: ChrX:74304998-74311862 bp, + strand  Genetic Position: ChrX, 37.97 cM, cytoband B-C1
Germline Transmission:  Earliest citation of germline transmission: J:79454
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe coding regions of exons 1 through 4 were replaced by a cassette containing lacZ followed by a floxed neo. Protein was undetected by Western blot analysis of brain tissue obtained from male hemizygous mice. (J:79454)
View phenotypes for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdi1 Mutation:  1 strain or line available
Original:  J:79454 D'Adamo P, et al., Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice. Hum Mol Genet. 2002 Oct 1;11(21):2567-80
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory