Pthlh^tm1Fbe
Targeted Allele Detail

Summary

• Symbol: Pthlh^tm1Fbe
• Name: parathyroid hormone-like peptide; targeted mutation 1, F Beck
• MGI ID: MGI:2388593
• Synonyms: PTHrP -
• Gene: Pthlh Location: Chr6:147153607-147165511 bp, - strand Genetic Position: Chr6, 78.19 cM, cytoband F-G
• Alliance: Pthlh^tm1Fbe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79622
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 4 was replaced with a neomycin selection cassette. (J:79622, J:112521)

Expression

In Structures Affected by this Mutation:

16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pthlh Mutation: 19 strains or lines available

References

• Original: J:79622 Tucci J, et al., The role of fetal parathyroid hormone-related protein in transplacental calcium transport. J Mol Endocrinol. 1996 Oct;17(2):159-64
• All: 7 reference(s)