Tg(MtTGFA)42Lmb
Transgene Detail
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| Symbol: |
Tg(MtTGFA)42Lmb |
| Name: |
transgene insertion 42, Glenn Merlino |
| MGI ID: |
MGI:2388567 |
| Synonyms: |
line MT42, MT42, MT-TGF-alpha, MT/TGF-alpha line MT42, TGF-alpha, Tg(Mt1-TGFA)42Lmb |
| Transgene: |
Tg(MtTGFA)42Lmb Location: unknown
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| Alliance: |
Tg(MtTGFA)42Lmb page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(MtTGFA)42Lmb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
TGFA (7039) |
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Mutation details: This transgene contains the inducible mouse Mt1 (metallothionein) promoter, cDNA of the wild-type allele of the human TGFA (transforming growth factor alpha) gene, and a human growth hormone polyadenylation signal. Line 100, carrying 10 copies of the transgene was also produced (see
Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:28452 Jhappan C, et al., TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas. Cell. 1990 Jun 15;61(6):1137-46 |
| All: |
39 reference(s) |
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Analysis Tools
