About   Help   FAQ
Kcnj1tm1Ges
Targeted Allele Detail
Nomenclature
Symbol: Kcnj1tm1Ges
Name: potassium inwardly-rectifying channel, subfamily J, member 1; targeted mutation 1, Gary E Shull
MGI ID: MGI:2388372
Synonyms: Romk-, ROMK(-)
Gene: Kcnj1  Location: Chr9:32372418-32399192 bp, + strand  Genetic Position: Chr9, 17.69 cM
Kcnj1tm1Ges/Kcnj1tm1Ges mice exhibit hydronephrosis

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79354
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kcnj1 Mutation:  3 strains or lines available
References
Original:  J:79354 Lorenz JN, et al., Impaired Renal NaCl Absorption in Mice Lacking the ROMK Potassium Channel, a Model for Type II Bartter's Syndrome. J Biol Chem. 2002 Oct 4;277(40):37871-80
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory