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Targeted Allele Detail
Symbol: Eportm1Jni
Name: erythropoietin receptor; targeted mutation 1, James N Ihle
MGI ID: MGI:2388345
Synonyms: EporH, Epor-H, H
Gene: Epor  Location: Chr9:21958899-21963576 bp, - strand  Genetic Position: Chr9, 7.93 cM
Germline Transmission:  Earliest citation of germline transmission: J:70036
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was truncated by replacement of exon 8 sequences encoding the distal half of the cytoplasmic domain with a neomycin resistance cassette. Expression of the mutant allele was confirmed by RT-PCR analysis of bone marrow RNA from homozygous mutant animals. (J:70036)
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Epor Mutation:  4 strains or lines available
Original:  J:70036 Zang H, et al., The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis. EMBO J. 2001 Jun 15;20(12):3156-66
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.01
The Jackson Laboratory