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Ntf3tm1Mpin
Targeted Allele Detail
Nomenclature
Symbol: Ntf3tm1Mpin
Name: neurotrophin 3; targeted mutation 1, Michael Meyer
MGI ID: MGI:2388319
Synonyms: NT-3 -
Gene: Ntf3  Location: Chr6:126101412-126166910 bp, - strand  Genetic Position: Chr6, 60.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79302
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe endogenous locus was disrupted by the insertion of a neomycin selection cassette via homologous recombination. Northern blot analysis showed transcript levels to be reduced by approximately 50% in heterozygous mutant mice. (J:79302)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntf3 Mutation:  14 strains or lines available
References
Original:  J:79302 Airaksinen MS, et al., Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation. Neuron. 1996 Feb;16(2):287-95
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory