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Sh2d1atm1Pls
Targeted Allele Detail
Nomenclature
Symbol: Sh2d1atm1Pls
Name: SH2 domain protein 1A; targeted mutation 1, Pamela L Schwartzberg
MGI ID: MGI:2388241
Synonyms: SAP-
Gene: Sh2d1a  Location: ChrX:42502453-42523697 bp, + strand  Genetic Position: ChrX, 23.2 cM, cytoband A5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:70032
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sh2d1a Mutation:  2 strains or lines available
References
Original:  J:70032 Czar MJ, et al., Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7449-54
All:  42 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory