About   Help   FAQ
Gpr132tm1Witt
Targeted Allele Detail
Nomenclature
Symbol: Gpr132tm1Witt
Name: G protein-coupled receptor 132; targeted mutation 1, Owen N Witte
MGI ID: MGI:2388138
Synonyms: G2A-
Gene: Gpr132  Location: Chr12:112850873-112868228 bp, - strand  Genetic Position: Chr12, 61.25 cM, cytoband F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69473
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exon 2 (98% of the total coding sequence) with an IRES-lacZ-PGK-neo cassette. Absence of gene expression was confirmed by RT-PCR analysis of pre-B and -T cells from homozygous mutant animals. (J:69473)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 9 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gpr132 Mutation:  16 strains or lines available
References
Original:  J:69473 Le LQ, et al., Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity. 2001 May;14(5):561-71
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/09/2018
MGI 6.12
The Jackson Laboratory