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Targeted Allele Detail
Symbol: Cx3cl1tm1Lira
Name: chemokine (C-X3-C motif) ligand 1; targeted mutation 1, Sergio A Lira
MGI ID: MGI:2388041
Synonyms: fractalkine-
Gene: Cx3cl1  Location: Chr8:94772009-94782427 bp, + strand  Genetic Position: Chr8, 46.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:68831
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire coding region of the gene was replaced with a neomycin resistance cassette via homologous recombination. Northern blot analysis of brain mRNA from homozygous mutant animals did not detect gene expression. Immunohistochemical analysis of brain sections from homozygous animals confirmed the absence of gene expression. (J:68831)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cx3cl1 Mutation:  19 strains or lines available
Original:  J:68831 Cook DN, et al., Generation and analysis of mice lacking the chemokine fractalkine. Mol Cell Biol. 2001 May;21(9):3159-65
All:  9 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
The Jackson Laboratory