Smarcb1^tm1Mya
Targeted Allele Detail

Summary

• Symbol: Smarcb1^tm1Mya
• Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; targeted mutation 1, Moshe Yaniv
• MGI ID: MGI:2387974
• Synonyms: SNF5^-, SNF5^lacZ
• Gene: Smarcb1 Location: Chr10:75732603-75757448 bp, - strand Genetic Position: Chr10, 38.61 cM
• Alliance: Smarcb1^tm1Mya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:68501
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was disrupted by replacement of exons 1 and 2 with a lacZ-PGK-neo cassette. Beta gallctosidase is expressed from this allele under the control of the endogenous promoter. (J:68501)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smarcb1 Mutation: 22 strains or lines available

References

• Original: J:68501 Klochendler-Yeivin A, et al., The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 2000 Dec;1(6):500-6
• All: 4 reference(s)