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Targeted Allele Detail
Symbol: Crlf1tm1Wsa
Name: cytokine receptor-like factor 1; targeted mutation 1, Warren S Alexander
MGI ID: MGI:2387956
Synonyms: NR6-
Gene: Crlf1  Location: Chr8:70493158-70504081 bp, + strand  Genetic Position: Chr8, 34.15 cM, cytoband C1
Germline Transmission:  Earliest citation of germline transmission: J:55482
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe majority of the coding region of the gene was replaced with a neomycin resistance cassette via homologous recombination. Northern blot analysis of lung, kidney, head, and limbs from homozygous mutant animals did not detect gene expression. (J:55482)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crlf1 Mutation:  8 strains or lines available
Original:  J:55482 Alexander WS, et al., Suckling defect in mice lacking the soluble haemopoietin receptor NR6. Curr Biol. 1999 Jun 3;9(11):605-8
All:  2 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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