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Msh2tm1Whl
Targeted Allele Detail
Nomenclature
Symbol: Msh2tm1Whl
Name: mutS homolog 2; targeted mutation 1, Wen-Hwa Lee
MGI ID: MGI:2387935
Synonyms: Msh2-
Gene: Msh2  Location: Chr17:87672330-87723713 bp, + strand  Genetic Position: Chr17, 57.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79016
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 3' portion of exon 3 was replaced by a neomycin selection cassette inserted by homologous recombination. (J:79016)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Msh2 Mutation:  84 strains or lines available
References
Original:  J:79016 Nikitin AY, et al., Cell Lineage-specific Effects Associated with Multiple Deficiencies of Tumor Susceptibility Genes in Msh2(-/-)Rb(+/-) Mice. Cancer Res. 2002 Sep 15;62(18):5134-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory