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Adcy5tm1Plhn
Targeted Allele Detail
Nomenclature
Symbol: Adcy5tm1Plhn
Name: adenylate cyclase 5; targeted mutation 1, Pyung-Lim Han
MGI ID: MGI:2387896
Synonyms: AC5-
Gene: Adcy5  Location: Chr16:35155636-35304549 bp, + strand  Genetic Position: Chr16, 24.71 cM, cytoband B-5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79146
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe 3' portion of exon 2 was replaced by a neomycin selection cassette inserted by homologous recombination. Northern and Western blot analyses confirmed the absence of transcript and protein in homozygous mutant mice. (J:79146)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy5 Mutation:  26 strains or lines available
References
Original:  J:79146 Lee KW, et al., Impaired d2 dopamine receptor function in mice lacking type 5 adenylyl cyclase. J Neurosci. 2002 Sep 15;22(18):7931-40
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory