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Tnni3tm1Jww
Targeted Allele Detail
Nomenclature
Symbol: Tnni3tm1Jww
Name: troponin I, cardiac 3; targeted mutation 1, Jeffery W Walker
MGI ID: MGI:2387868
Synonyms: cTnI-
Gene: Tnni3  Location: Chr7:4518305-4524229 bp, - strand  Genetic Position: Chr7, 2.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:53628
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire gene (exon 1-8) was replaced with a neomycin resistance gene via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by Western blot analysis. (J:53628)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnni3 Mutation:  3 strains or lines available
References
Original:  J:53628 Huang X, et al., Cardiac troponin I gene knockout: a mouse model of myocardial troponin I deficiency [see comments]. Circ Res. 1999 Jan 8-22;84(1):1-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/07/2015
MGI 5.21
The Jackson Laboratory