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Mixl1tm1.1Robb
Targeted Allele Detail
Nomenclature
Symbol: Mixl1tm1.1Robb
Name: Mix1 homeobox-like 1 (Xenopus laevis); targeted mutation 1.1, Lorraine Robb
MGI ID: MGI:2387829
Synonyms: Mixl1deltaneo
Gene: Mixl1  Location: Chr1:180693043-180697034 bp, - strand  Genetic Position: Chr1, 84.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77443
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
 
Mutation detailsThe floxed neo cassette was excised from Mixl1tm1Robb via in vivo cre mediated recombination. The previously inserted GFP sequence remained in place of the coding region of exon 1. (J:77443)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 10 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mixl1 Mutation:  7 strains or lines available
References
Original:  J:77443 Hart AH, et al., Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory