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Sftpctm1Swg
Targeted Allele Detail
Nomenclature
Symbol: Sftpctm1Swg
Name: surfactant associated protein C; targeted mutation 1, Stephan W Glasser
MGI ID: MGI:2387813
Synonyms: SP-C(-)
Gene: Sftpc  Location: Chr14:70520941-70524081 bp, - strand  Genetic Position: Chr14, 36.32 cM
Airspace remodeling, stromal thickening and monocytic infiltration in the lungs of Sftpctm1Swg/Sftpctm1Swg mice

Show the 6 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69619
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sftpc Mutation:  4 strains or lines available
Notes
ES cell line = D3R.

References
Original:  J:69619 Glasser SW, et al., Altered stability of pulmonary surfactant in SP-C-deficient mice. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6366-71
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory