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Nmbrtm1Hoh
Targeted Allele Detail
Nomenclature
Symbol: Nmbrtm1Hoh
Name: neuromedin B receptor; targeted mutation 1, Hiroko Ohki-Hamazaki
MGI ID: MGI:2387767
Synonyms: NBR-
Gene: Nmbr  Location: Chr10:14705591-14770850 bp, + strand  Genetic Position: Chr10, 5.5 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52410
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced by a neomycin selection cassette inserted by homologous recombination. The absence and functional ablation of the receptor were confirmed by RT-PCR analysis and binding assays. (J:52410)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nmbr Mutation:  16 strains or lines available
References
Original:  J:52410 Ohki-Hamazaki H, et al., Functional properties of two bombesin-like peptide receptors revealed by the analysis of mice lacking neuromedin B receptor. J Neurosci. 1999 Feb 1;19(3):948-54
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/07/2017
MGI 6.11
The Jackson Laboratory