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H2afztm1Ily
Targeted Allele Detail
Nomenclature
Symbol: H2afztm1Ily
Name: H2A histone family, member Z; targeted mutation 1, Ian Lyons
MGI ID: MGI:2387764
Synonyms: H2A.Z-
Gene: H2afz  Location: Chr3:137864487-137866922 bp, + strand  Genetic Position: Chr3, 63.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71146
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe promoter regions and exons 1 and 2 were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were detected by PCR genotyping up to day E6.5. (J:71146)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any H2afz Mutation:  16 strains or lines available
References
Original:  J:71146 Faast R, et al., Histone variant H2A.Z is required for early mammalian development. Curr Biol. 2001 Aug 7;11(15):1183-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory