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Cdh6tm1Nosu
Targeted Allele Detail
Summary
Symbol: Cdh6tm1Nosu
Name: cadherin 6; targeted mutation 1, Noriko Osumi
MGI ID: MGI:2387681
Gene: Cdh6  Location: Chr15:13028787-13173761 bp, - strand  Genetic Position: Chr15, 6.11 cM
Alliance: Cdh6tm1Nosu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:67150
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe gene was disrupted by insertion of a PGK-neo cassette (in reverse orientation) into exon 1. Absence of gene expression in homozygous mutants was confirmed by Western blot analysis of whole brain homogenates from postnatal day 7 animals. (J:67150)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh6 Mutation:  40 strains or lines available
References
Original:  J:67150 Inoue T, et al., Role of cadherins in maintaining the compartment boundary between the cortex and striatum during development. Development. 2001 Feb;128(4):561-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory