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Fut7tm1Jbl
Targeted Allele Detail
Nomenclature
Symbol: Fut7tm1Jbl
Name: fucosyltransferase 7; targeted mutation 1, John Lowe
MGI ID: MGI:2387664
Synonyms: FucT-VII (-)
Gene: Fut7  Location: Chr2:25423267-25426374 bp, + strand  Genetic Position: Chr2, 17.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35023
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Sequence encoding the catalytic domain was disrupted by the insertion of a PGK-neo cassette. (J:35023)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fut7 Mutation:  7 strains or lines available
References
Original:  J:35023 Maly P, et al., The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 1996 Aug 23;86(4):643-53
All:  45 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory