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Pthlhtm1Ack
Targeted Allele Detail
Nomenclature
Symbol: Pthlhtm1Ack
Name: parathyroid hormone-like peptide; targeted mutation 1, Andrew C Karaplis
MGI ID: MGI:2387462
Synonyms: Pthrpflox, PTHrPL2
Gene: Pthlh  Location: Chr6:147252101-147264167 bp, - strand  Genetic Position: Chr6, 78.19 cM, cytoband F-G
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:69396
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 4 was left flanked by single loxP sites after a downstream floxed selection cassette was removed via in vitro cre mediated excison. (J:69396)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pthlh Mutation:  4 strains or lines available
References
Original:  J:69396 He B, et al., Tissue-specific targeting of the pthrp gene: the generation of mice with floxed alleles. Endocrinology. 2001 May;142(5):2070-7
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory