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Targeted Allele Detail
Symbol: Dpttm1Hsh
Name: dermatopontin; targeted mutation 1, Hiroshi Shinkai
MGI ID: MGI:2387341
Synonyms: Dpt-
Gene: Dpt  Location: Chr1:164796644-164824266 bp, + strand  Genetic Position: Chr1, 72.12 cM, cytoband H2
Germline Transmission:  Earliest citation of germline transmission: J:78845
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was demonstrated by RT-PCR and Western blot analysis of tail tissues. (J:78845)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dpt Mutation:  5 strains or lines available
Original:  J:78845 Takeda U, et al., Targeted disruption of dermatopontin causes abnormal collagen fibrillogenesis. J Invest Dermatol. 2002 Sep;119(3):678-83
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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