About   Help   FAQ
Stk11tm1Tpm
Targeted Allele Detail
Nomenclature
Symbol: Stk11tm1Tpm
Name: serine/threonine kinase 11; targeted mutation 1, Tomi P Makela
MGI ID: MGI:2387003
Synonyms: Lkb1-
Gene: Stk11  Location: Chr10:80115803-80130682 bp, + strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:70892
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 2 through 7 were replaced with a neomycin selection cassette by homologous recombination. (J:70892)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk11 Mutation:  5 strains or lines available
References
Original:  J:70892 Ylikorkala A, et al., Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science. 2001 Aug 17;293(5533):1323-6
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory