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Il6sttm1Thir
Targeted Allele Detail
Nomenclature
Symbol: Il6sttm1Thir
Name: interleukin 6 signal transducer; targeted mutation 1, Toshio Hirano
MGI ID: MGI:2386991
Synonyms: F759, gp130F759
Gene: Il6st  Location: Chr13:112464070-112510086 bp, + strand  Genetic Position: Chr13, 63.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:59922
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (knock-in)
Mutation:    Nucleotide substitutions
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il6st Mutation:  10 strains or lines available
References
Original:  J:59922 Ohtani T, et al., Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity. 2000 Jan;12(1):95-105
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory