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Lbx1tm1Thbr
Targeted Allele Detail
Summary
Symbol: Lbx1tm1Thbr
Name: ladybird homeobox 1; targeted mutation 1, Thomas Braun
MGI ID: MGI:2386948
Synonyms: Lbx1(-)
Gene: Lbx1  Location: Chr19:45221123-45224251 bp, - strand  Genetic Position: Chr19, 38.61 cM, cytoband D
Alliance: Lbx1tm1Thbr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:57891
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA cassette containing IRES-lacZ and PGK-neo replaced the homeobox encoding region of exon 2 and 1 kb of fragment of the polyadenylation sequence. (J:57891)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 44 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lbx1 Mutation:  13 strains or lines available
References
Original:  J:57891 Schafer K, et al., Early specification of limb muscle precursor cells by the homeobox gene Lbx1h. Nat Genet. 1999 Oct;23(2):213-6
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory