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Tg(Myh6-cre)2182Mds
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-cre)2182Mds
Name: transgene insertion 2182, Michael D Schneider
MGI ID: MGI:2386742
Synonyms: alphaMhc-Cre, alpha-MHC-Cre+, alphaMyHC-Cre, MCH-cre, MHCalphaCre, MHCcre, MHC-Cre, Tg(Myhca-cre)2182Mds
Transgene: Tg(Myh6-cre)2182Mds  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe transgenic construct contained the Myh7 3' untranslated region, the Myhca promoter, Myhca noncoding exons 1 and 2, and the exon 3 splice acceptor site 180 bp upstream and driving the expression of the cre recombinase sequence. The Myhca promoter drives expression in cardiac tissue. (J:67908)
Generation of the Rhebtm1.1Otsu allele
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myh6     Summary of all recombinase alleles driven by Myh6.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 7 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
References
Original:  J:67908 Agah R, et al., Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest. 1997 Jul 1;100(1):169-79
All:  337 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/13/2020
MGI 6.16
The Jackson Laboratory