Tg(Myh6-cre)2182Mds
Transgene Detail

Nomenclature

• Symbol: Tg(Myh6-cre)2182Mds
• Name: transgene insertion 2182, Michael D Schneider
• MGI ID: MGI:2386742
• Synonyms: alphaMhc-Cre, alpha-MHC-Cre⁺, alphaMyHC-Cre, MCH-cre, MHCalphaCre, MHCcre, MHC-Cre, Tg(Myhca-cre)2182Mds
• Transgene: Tg(Myh6-cre)2182Mds Location: unknown

Transgene origin

• Strain of Origin: FVB/N

Transgene description

Transgene Type: Transgenic (Recombinase) Mutation: Insertion Mutation details: The transgenic construct contained the Myh7 3' untranslated region, the Myhca promoter, Myhca noncoding exons 1 and 2, and the exon 3 splice acceptor site 180 bp upstream and driving the expression of the cre recombinase sequence. The Myhca promoter drives expression in cardiac tissue. (J:67908)

Generation of the Rheb^tm1.1Otsu allele

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myh6     Summary of all recombinase alleles driven by Myh6.

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available

References

• Original: J:67908 Agah R, et al., Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo. J Clin Invest. 1997 Jul 1;100(1):169-79
• All: 257 reference(s)