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Targeted Allele Detail
Symbol: Ppardtm1.1Rev
Name: peroxisome proliferator activator receptor delta; targeted mutation 1.1, Ronald M Evans
MGI ID: MGI:2386684
Synonyms: Ppardelta-
Gene: Ppard  Location: Chr17:28232754-28301469 bp, + strand  Genetic Position: Chr17, 14.64 cM
Pathologies of Ppardtm1.1Rev/Ppardtm1.1Rev mouse placentas

Show the 2 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:73557
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsExon 4, which encodes the amino terminal portion of the DNA binding domain was excised along with a downstream neo cassette via the expression of cre recombinase in vitro. (J:73557)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppard Mutation:  60 strains or lines available
Original:  J:73557 Barak Y, et al., Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):303-8
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory