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Targeted Allele Detail
Symbol: Vcam1tm3Flv
Name: vascular cell adhesion molecule 1; targeted mutation 3, Richard A Flavell
MGI ID: MGI:2386559
Synonyms: vcam-1delta
Gene: Vcam1  Location: Chr3:116109949-116129688 bp, - strand  Genetic Position: Chr3, 50.17 cM
Germline Transmission:  Earliest citation of germline transmission: J:68147
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe cytokine responsive promoter region and exon 1 were deleted by cre mediated recombination in vivo. Protein was undected in mutant mice via immunohistochemical analysis of lung sections. (J:68147)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vcam1 Mutation:  23 strains or lines available
Original:  J:68147 Koni PA, et al., Conditional Vascular Cell Adhesion Molecule 1 Deletion in Mice. Impaired lymphocyte migration to bone marrow. J Exp Med. 2001 Mar 19;193(6):741-54
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory