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Wrntm1Lgu
Targeted Allele Detail
Nomenclature
Symbol: Wrntm1Lgu
Name: Werner syndrome homolog (human); targeted mutation 1, Leonard Guarente
MGI ID: MGI:2386438
Synonyms: WRN-
Gene: Wrn  Location: Chr8:33234384-33385527 bp, - strand  Genetic Position: Chr8, 20.3 cM, cytoband A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:61567
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wrn Mutation:  8 strains or lines available
References
Original:  J:61567 Lombard DB, et al., Mutations in the WRN gene in mice accelerate mortality in a p53-null background. Mol Cell Biol. 2000 May;20(9):3286-91
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory