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Smad4tm2.2Cxd
Targeted Allele Detail
Nomenclature
Symbol: Smad4tm2.2Cxd
Name: SMAD family member 4; targeted mutation 2.2, Chu-Xia Deng
MGI ID: MGI:2386394
Synonyms: Smad4delta8
Gene: Smad4  Location: Chr18:73639009-73703780 bp, - strand  Genetic Position: Chr18, 49.51 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75140
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe entire floxed fragment, containing exon 8 and a neo cassette, was excised via the in vivo expression of cre recombinase. A single loxP site was left downstream of exon 9. (J:75140)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad4 Mutation:  12 strains or lines available
References
Original:  J:75140 Yang X, et al., Generation of Smad4/Dpc4 conditional knockout mice. Genesis. 2002 Feb;32(2):80-1
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory