Smad4^tm2.2Cxd
Targeted Allele Detail

Summary

• Symbol: Smad4^tm2.2Cxd
• Name: SMAD family member 4; targeted mutation 2.2, Chu-Xia Deng
• MGI ID: MGI:2386394
• Synonyms: Smad4^delta8
• Gene: Smad4 Location: Chr18:73772080-73836851 bp, - strand Genetic Position: Chr18, 49.51 cM
• Alliance: Smad4^tm2.2Cxd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75140
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The entire floxed fragment, containing exon 8 and a neo cassette, was excised via the in vivo expression of cre recombinase. A single loxP site was left downstream of exon 9. (J:75140)

Expression

In Mice Carrying this Mutation:

41 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Smad4 Mutation: 43 strains or lines available

References

• Original: J:75140 Yang X, et al., Generation of Smad4/Dpc4 conditional knockout mice. Genesis. 2002 Feb;32(2):80-1
• All: 7 reference(s)