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Targeted Allele Detail
Symbol: Kat2atm1Nkt
Name: K(lysine) acetyltransferase 2A; targeted mutation 1, Yoshihiro Nakatani
MGI ID: MGI:2386309
Synonyms: PCAF-B-
Gene: Kat2a  Location: Chr11:100704746-100712465 bp, - strand  Genetic Position: Chr11, 63.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:65264
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced the genomic region encoding amino acids 472 through 830 of the carboxy terminus of the encoded protein. No protein product is expressed from this allele as determined by Western blot analysis. (J:65264)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kat2a Mutation:  17 strains or lines available
Original:  J:65264 Yamauchi T, et al., Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11303-6
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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