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Slc6a3tm1Mca
Targeted Allele Detail
Nomenclature
Symbol: Slc6a3tm1Mca
Name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; targeted mutation 1, Marc G Caron
MGI ID: MGI:2386303
Synonyms: DAT-, DAT-KO
Gene: Slc6a3  Location: Chr13:73536747-73578672 bp, + strand  Genetic Position: Chr13, 40.1 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:31328
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a3 Mutation:  34 strains or lines available
References
Original:  J:31328 Giros B, et al., Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 1996 Feb 15;379(6566):606-12
All:  78 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory