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Rev3ltm1Msn
Targeted Allele Detail
Nomenclature
Symbol: Rev3ltm1Msn
Name: REV3 like, DNA directed polymerase zeta catalytic subunit; targeted mutation 1, Michael S Neuberger
MGI ID: MGI:2386282
Synonyms: mRev3N
Gene: Rev3l  Location: Chr10:39732118-39875211 bp, + strand  Genetic Position: Chr10, 21.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65202
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsThe insertion of a neomycin selection cassette disrupted an exon encoding a portion of the carboxy terminal DNA polymerase domain. (J:65202)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rev3l Mutation:  48 strains or lines available
References
Original:  J:65202 Bemark M, et al., Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. Curr Biol. 2000 Oct 5;10(19):1213-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory