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Mesp1/Mesp2tm1Ysa
Targeted Allele Detail
Nomenclature
Symbol: Mesp1/Mesp2tm1Ysa
Name: mesoderm posterior 1; targeted mutation 1, Yumiko Saga
MGI ID: MGI:2386200
Synonyms: Mesp1, p2-del
Gene: Mesp1  Location: Chr7:79792241-79793788 bp, - strand  Genetic Position: Chr7, 45.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62984
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation detailsA single targeting event replaced a 20 kb region containing Mesp1 and Mesp2 with a PGK-neo cassette via homologous recombination. (J:62984)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mesp1 Mutation:  11 strains or lines available
References
Original:  J:62984 Kitajima S, et al., MesP1 and MesP2 are essential for the development of cardiac mesoderm. Development. 2000 Aug;127(15):3215-26
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory