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Tcof1tm1Mjd
Targeted Allele Detail
Nomenclature
Symbol: Tcof1tm1Mjd
Name: Treacher Collins Franceschetti syndrome 1, homolog; targeted mutation 1, Michael J Dixon
MGI ID: MGI:2386185
Synonyms: Tcof1-
Gene: Tcof1  Location: Chr18:60813755-60848971 bp, - strand  Genetic Position: Chr18, 34.41 cM
Analysis of Tcof1tm1Mjd/Tcof1+ embryos

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:62928
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 2 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcof1 Mutation:  45 strains or lines available
References
Original:  J:62928 Dixon J, et al., Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, treacher collins syndrome. Hum Mol Genet. 2000 Jun 12;9(10):1473-80
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory