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Nfe2l1tm1Tow
Targeted Allele Detail
Nomenclature
Symbol: Nfe2l1tm1Tow
Name: nuclear factor, erythroid derived 2,-like 1; targeted mutation 1, Timothy Townes
MGI ID: MGI:2385936
Synonyms: Lcrf1tm1uab, Nfe2l1tm1Tmt
Gene: Nfe2l1  Location: Chr11:96817431-96829955 bp, - strand  Genetic Position: Chr11, 60.12 cM, cytoband D-E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:39447
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details3.5 kb of genomic sequence containing exons 3, 4, 5 and part of 6 was replaced with a neomycin selection cassette. RT-PCR analysis on 8 day old embryoid bodies derived from homozygous ES cells confirmed that no transcript is expressed from this allele. (J:39447)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l1 Mutation:  12 strains or lines available
References
Original:  J:39447 Farmer SC, et al., The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. Genes Dev. 1997 Mar 15;11(6):786-98
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory