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Myl2tm1(cre)Krc
Targeted Allele Detail
Nomenclature
Symbol: Myl2tm1(cre)Krc
Name: myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
MGI ID: MGI:2385922
Synonyms: MLC-2v -, Mlc2v-cre, MLC2v-cre, MLC2vcreKI
Gene: Myl2  Location: Chr5:122100951-122113472 bp, + strand  Genetic Position: Chr5, 62.16 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:45125
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myl2     Summary of all recombinase alleles driven by Myl2.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myl2 Mutation:  2 strains or lines available
References
Original:  J:45125 Chen J, et al., Selective requirement of myosin light chain 2v in embryonic heart function. J Biol Chem. 1998 Jan 9;273(2):1252-6
All:  85 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory