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Targeted Allele Detail
Symbol: Nr6a1tm1Coo
Name: nuclear receptor subfamily 6, group A, member 1; targeted mutation 1, Austin J Cooney
MGI ID: MGI:2385846
Synonyms: GCNF-
Gene: Nr6a1  Location: Chr2:38723370-38927688 bp, - strand  Genetic Position: Chr2, 24.42 cM
Germline Transmission:  Earliest citation of germline transmission: J:67377
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe exon encoding the DNA-binding domain was replaced with a neomycin selection cassette. Transcript was undetected via in situ hybridization of homozygous mutant embryos. (J:67377)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr6a1 Mutation:  129 strains or lines available
Original:  J:67377 Chung AC, et al., Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan;21(2):663-77
All:  4 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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