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Krt6a/Krt6btm1Cou
Targeted Allele Detail
Nomenclature
Symbol: Krt6a/Krt6btm1Cou
Name: keratin 6A; targeted mutation 1, Pierre A Coulombe
MGI ID: MGI:2385807
Synonyms: K6alpha/beta null
Gene: Krt6a  Location: Chr15:101689932-101694307 bp, - strand  Genetic Position: Chr15, 56.97 cM
Growth retardation and tongue blisters in Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64033
Parent Cell Line:  CK35 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt6a Mutation:  0 strains or lines available
References
Original:  J:64033 Wong P, et al., Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa. J Cell Biol. 2000 Aug 21;150(4):921-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory