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Itga2btm1Tlr
Targeted Allele Detail
Nomenclature
Symbol: Itga2btm1Tlr
Name: integrin alpha 2b; targeted mutation 1, Diana Tronik-Le Roux
MGI ID: MGI:2385793
Synonyms: alphaIIb-
Gene: Itga2b  Location: Chr11:102453297-102470122 bp, - strand  Genetic Position: Chr11, 66.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63961
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itga2b Mutation:  0 strains or lines available
References
Original:  J:63961 Tronik-Le Roux D, et al., Thrombasthenic mice generated by replacement of the integrin alpha(IIb) gene: demonstration that transcriptional activation of this megakaryocytic locus precedes lineage commitment. Blood. 2000 Aug 15;96(4):1399-408
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory