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Ltb4r1tm1Bodd
Targeted Allele Detail
Nomenclature
Symbol: Ltb4r1tm1Bodd
Name: leukotriene B4 receptor 1; targeted mutation 1, Bodduluri Haribabu
MGI ID: MGI:2385781
Synonyms: BLTR-, BTL1-
Gene: Ltb4r1  Location: Chr14:55765962-55768494 bp, + strand  Genetic Position: Chr14, 28.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:63874
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details706 bp of the coding region was replaced with a PGK-neo cassette via homologous recombination resulting in the deletion of amino acids 81-316 from the encoded protein. Homozygous mutant animals were identified by PCR genotype analysis and Southern blot. (J:63874)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ltb4r1 Mutation:  13 strains or lines available
References
Original:  J:63874 Haribabu B, et al., Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis [see comments]. J Exp Med. 2000 Aug 7;192(3):433-8
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory