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Trp63tm3.2Brd
Targeted Allele Detail
Nomenclature
Symbol: Trp63tm3.2Brd
Name: transformation related protein 63; targeted mutation 3.2, Allan Bradley
MGI ID: MGI:2385474
Synonyms: p63Brdm3
Gene: Trp63  Location: Chr16:25683763-25892102 bp, + strand  Genetic Position: Chr16, 17.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75125
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe ubiquitous expression of cre recombinase resulted in the excision of the both the floxed region containing exons 5 through 7 and the neo cassette from Trp63tm3Brd. Exons 5 through 7, encode the DNA-binding domain. (J:75125)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trp63 Mutation:  13 strains or lines available
References
Original:  J:75125 Mills AA, et al., Conditional inactivation of p63 by Cre-mediated excision. Genesis. 2002 Feb;32(2):138-41
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory