About   Help   FAQ
Targeted Allele Detail
Symbol: Sox9tm1.1Gsr
Name: SRY (sex determining region Y)-box 9; targeted mutation 1.1, Gerd Scherer
MGI ID: MGI:2385469
Synonyms: Sox9-delex2,3
Gene: Sox9  Location: Chr11:112782224-112787760 bp, + strand  Genetic Position: Chr11, 77.27 cM
Germline Transmission:  Earliest citation of germline transmission: J:75124
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThis allele lacks exons 2 and 3, which encode a portion of the DNA-binding high mobility group domain and the entire transactivation domain. It can be derived from Sox9tm1Gsr by cre recombinase excision of the loxP-flanked region containing exons 2 and 3 or from Sox9tm2Gsr by simultaneous excision of exons 2 and 3 and of a loxP-flanked neo cassette (which has been deleted in Sox9tm1Gsr). (J:75124)
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox9 Mutation:  17 strains or lines available
Original:  J:75124 Kist R, et al., Conditional inactivation of Sox9: a mouse model for campomelic dysplasia. Genesis. 2002 Feb;32(2):121-3
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory