About   Help   FAQ
Hfetm1.1Nca
Targeted Allele Detail
Nomenclature
Symbol: Hfetm1.1Nca
Name: hemochromatosis; targeted mutation 1.1, Nancy C Andrews
MGI ID: MGI:2385350
Synonyms: C282Y, Hfe845A, (Y)
Gene: Hfe  Location: Chr13:23702034-23710854 bp, - strand  Genetic Position: Chr13, 9.88 cM, cytoband A2-A4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78536
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (knock-in)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hfe Mutation:  11 strains or lines available
References
Original:  J:78536 Levy JE, et al., The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood. 1999 Jul 1;94(1):9-11
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory