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Scnn1atm1.2Hum
Targeted Allele Detail
Nomenclature
Symbol: Scnn1atm1.2Hum
Name: sodium channel, nonvoltage-gated 1 alpha; targeted mutation 1.2, Edith Hummler
MGI ID: MGI:2384529
Synonyms: Scnn1atm2
Gene: Scnn1a  Location: Chr6:125320659-125344943 bp, + strand  Genetic Position: Chr6, 59.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75110
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA floxed region containing exon 1 was excised by breeding mice possessing Scnn1atm1.1Ipt with transgenic mice expressing Cre under the contol of an EIIa promoter. (J:75110)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scnn1a Mutation:  6 strains or lines available
References
Original:  J:75110 Hummler E, et al., Conditional gene targeting of the Scnn1a (alphaENaC) gene locus. Genesis. 2002 Feb;32(2):169-72
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory