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Targeted Allele Detail
Symbol: Tgfbr2tm1.1Hlm
Name: transforming growth factor, beta receptor II; targeted mutation 1.1, Harold L Moses
MGI ID: MGI:2384512
Synonyms: -Exon2/-Neor
Gene: Tgfbr2  Location: Chr9:116087695-116175363 bp, - strand  Genetic Position: Chr9, 68.39 cM
Germline Transmission:  Earliest citation of germline transmission: J:75073
Parent Cell Line:  TL1/TL-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis allele is derived from Tgfbr2tm1Hlm. Expression of cre recombinase at the one cell stage resulted in the excision of the floxed region containing exon 2, neo, and an intervening loxP site. (J:75073)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgfbr2 Mutation:  7 strains or lines available
Original:  J:75073 Chytil A, et al., Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis. 2002 Feb;32(2):73-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory